nature of their products and marketing practices

Hi. The unsubscribe rate is an important metric that signals how relevant and useful your emails are to your audience. If it's high, you might want to reconsider your newsletter frequency or content. Audience segmentation has helped me - it allowed me to send more targeted emails and reduce the number of unsubscribes. The email marketing kpi article may give you the insight you need into how unsubscribe rate can affect other KPIs, so I recommend reading it.